Moyamoya Disease

[dr_manjiri_21]

hello, every one,
i would like to know about moyamoya disease. what is its aetiology,clinical features .

[physiobob]

Originally Posted by dr_manjiri_21

hello, every one,
i would like to know about moyamoya disease. what is its aetiology,clinical features .

Take a look at the following thread on Moyamoya disease /forum/showthread.php?t=306&highlight=moya (Moya Moya disease)

[monish_physio]

Definition:-
Moyamoya Disease is a progressive disease that affects the blood vessels
in the brain.

Description:-
-- It is characterized by the narrowing and/or closing of the main
arteries to the brain (usually the carotid arteries) just as they enter the skull.
The brain attempts to overcome this narrowing and subsequent reduction
in blood flow by enlarging other smaller blood vessels, a process called
forming collaterals.
-- In patients with Moyamoya Disease the enlargement
of some of the, usually small, vessels at the base of the brain (called
lenticulostriate arteries) leads to a pattern on an angiogram that somewhat
resembles a puff of smoke.
-- Moyamoya Disease is most common in the Asian
population and the term moyamoya comes from the Japanese word for
puff-of-smoke.

Features not so specific:-
--Patients with Moyamoya Disease are prone to strokes and brain hemorrhages.
-- Patients may come to medical attention either as children or adults and symptoms may vary widely. Medical treatments are often ineffective and surgery is frequently required
. The goal of surgery is to provide more blood flow in order to decrease
the future risk of stroke.
 Several procedures or combinations of procedures may
be tried. Some of the most common include an encephalo-duro-arterio-synangiosis
(EDAS), an intracranial to extracranial (EC-IC) bypass, and an encephalo-myo-
synangiosis (EMS).
 An EDAS involves placing an unaffected scalp artery directly on
the brain and allowing connections (collaterals) to develop between the artery and
the existing brain arteries, thus improving blood flow to the brain. An EMS uses
muscle from the side of the head (temporalis muscle), which has a good blood
supply, to accomplish the same purpose.
 An EC-IC bypass creates a direct connection
between a scalp artery and a brain (intracranial) artery.